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Summary and outlook In recent years, substantial clinical and basic research has advanced our understanding of heat stress-induced liver injury, yet its complex pathogenesischaracterized by interconnected mechanisms including hyperthermia-induced direct hepatocyte damage, oxidative stress, inflammatory cascades, and diverse programmed cell death modes (apoptosis, necroptosis, pyroptosis, ferroptosis)remains incompletely elucidated

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Rhodiola and Withania for Neuroprotection in Stroke and Their Synergistic Effect on Neurogenesis Rhodiola in Experimental Models of Stroke A systematic review and meta-analysis of 15 preclinical studies of Rhodiola rosea extract and isolated salidroside and tyrosol suggest they can effectively treat ischemic stroke [377]